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People have been found to lose large amounts of weight on the drug in trials, but it is not approved by the FDA for this purpose
refer to the MHRA/EMC SmPC and NHS medicines information for full details
Abbreviations ADA: American Diabetes Association CV: Cardiovascular CVOTs: Cardiovascular outcome trials GLP-1RA: Glucagon-like peptide-1 receptor agonists HR: Hazard ratios MACE: Major cardiovascular events SGLT-2i: Sodiumglucose transporter-2 inhibitors T2DM: Type 2 diabetes mellitus References Giugliano D, Maiorino MI, Longo M, Bellastella G, Chiodini P, Esposito K
This is a household-level demand signal, not a niche-cohort marketing problem
#2: Adverse effects and long-term efficacy There have been quite a few studies measuring adherence among different groups and with different formulations, so the exact numbers vary
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