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All of the velocities are given by Michaelis-Menten kinetics, with the K m values taken from the literature, and where available, from human data
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Ongoing pharmacovigilance and real-world evidence collection will be important for further characterizing the risk-benefit profile in this diverse patient population
Microdosing may be especially relevant for people who are dose-sensitive or who want a steadier, slower pace of physiological change
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