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2021 NEJM) randomized 1,961 adults with overweight or obesity (without diabetes) to semaglutide 2.4 mg weekly or placebo for 68 weeks
its a first-in-class treatment that tackles both blood sugar control and weight management with remarkable effectiveness
The differences in adverse events across reporter type, sex, age, dose, indication, report year, onset time, and outcome subgroups were specifically investigated
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