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GLP-1 agonists and SGLT-2 inhibitors are recommended for high-risk individuals with type 2 diabetes, regardless of A1C levels, to: Reduce risk of heart attack, stroke, and other major adverse cardiovascular events (MACE)
Regular physical activity, such as aerobic exercise and strength training, can help increase energy expenditure and promote fat loss
Faseb J2010 Dec;24(12):5080-91
Part of what's happening is that the high-volume GLP-1 signal is dramatically slowing motility throughout the GI tract
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