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Investigational Drug Notice
L-carnitine dependent binding of the purified CarR protein to the intergenic region between carR and the consecutive carnitine catabolic operon was demonstrated ( A
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For metal-based complexes (e.g., Pt(IV), Cu(II)), thermodynamic stability varies significantly with ligand choice and pH, influencing both efficacy and metal ion leakage, which may cause off-target toxicity or catalytic unintended reactions [160, 161]
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