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We do not know how much of it is absorbed through the skin, but generally, barring a few chemicals such as hydroquinone, absorption from intact skin is minimal
Heres a nice picture to sum it all up for you visual learners: Signs and Symptoms of Acetaminophen Toxicity Clinical symptoms of an acute acetaminophen toxicity are strongly dependent on two things: time since ingestion and amount consumed
However, typical research protocols use 250-500mcg once or twice daily, often injected subcutaneously near the injury site
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