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In addition, acylcarnitine accelerates the degradation of the PD1 protein by promoting the acetylation of the E3 ubiquitin ligase FBXO38, revealing not only the mediating role of acylcarnitine in mitochondrial communication between platelets and B cells but also its epigenetic regulatory role in regulating mitochondrial function and PD1 degradation [43]

Journal of Zhejiang University - Science B 19

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Compared to livers from control mice, those from HFD-fed mice showed a significantly increased percentage of methylation at the CpG islands of CYP2R1 (Fig

D., Rao, M., Gilbertson, D