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Pharmacokinetics of luteolin and metabolites in rats

The three primaries human ApoE polymorphisms, ApoE2, ApoE3, and ApoE4, exhibit differential effects on A clearance and aggregation within the brain

CRISPR/Cas9 generation of ADH5 and GCLM cell lines HCT116 ADH5 , GCLM , TP53 ADH5 , and ADH5 GCLM cell lines were generated by targeting exon 3 of ADH5 (sgRNA: TGCTGGAATTGTGAAAGTGTT) and exon 1 of GCLM (sgRNA: ACGGGGAACCTGCTGAACTG) in the corresponding parental cell lines