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In addition, we assessed the expression of the key metformin responsive protein LKB1
Binding affinity data from Hruby and colleagues' foundational work at Arizona (published through the 1990s and 2000s in the Journal of Medicinal Chemistry) established that MT2 has substantially greater potency than alpha-MSH across the receptor panel, with a particularly pronounced gain at MC4R relative to MC1R
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10.1007/s12253-017-0228-0 Pathol Oncol Res
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