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Individual variability : Some patients may respond better than others, depending on genetics and metabolic profile

D., Xiong, B., Baibakov, B., Jimenez-Movilla, M

Results Targeting functional GCL to mitochondria decreases ROS To direct -glutamylcysteine synthesis to mitochondria, the full-length complementary DNA encoding the catalytic GCL subunit was fused with the mitochondrial-targeting signal of ornithine transcarbamylase