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Topiramate was first approved by the FDA in 1996 to treat epilepsy and migraine

While two other CYP76s expressed in ripening berries can also metabolize linalool, only CYP76F14 catalyzes the entire oxidative cascade from linalool to ( E )-8-carboxylinalool 69

According to the Pocket Manual of Therapy, the universal clinical scenario has been based for years on the hemodynamic protection of the glomerulus

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