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Imai, S., Armstrong, C

Not suitable for women who are pregnant or breastfeeding

Significant barriers still exist despite established safety profiles, such as high costs that restrict access worldwide, a lack of predictive biomarkers for treatment response, a lack of knowledge about the mechanistics of gut microbiota interactions, and an incomplete understanding of long-term safety, particularly with regard to thyroid and pancreatic effects

A healthier liver improves insulin processing and overall metabolism, supporting sustained weight management

In order to maintain intracellular glutamine-derived glutamate levels, NRF2-addicted cells exploit glutamine transporter, SLC1A5, to uptake more extracellular glutamine that is then converted to glutamate by glutaminase (Romero et al