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Both can be effective in weight loss, but in head-to-head trials, tirzepatide has a slight edge over semaglutide
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These are generally mild and transient, resolving within a few days without specific treatment
It has been the leading cause of death in the United States for essentially a century, and in 2025 it killed 694,708 Americans about one in five deaths more than every form of cancer combined
Side effect profiles overlap considerably but differ in intensity and frequency
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