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The SUSTAIN trials showed that semaglutide alone reduced A1C by 1.5-1.8 percentage points

There is a very narrow clinically safe range for selenium intake, too little and there are serious clinical consequences, too much and some overlapping as well as a different set of serious clinical complications occur

Kainer et al

Plenty of people maintain excellent results at 5 mg, 7.5 mg, or 10 mg and never touch the maximum dose