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When to seek medical advice : Patients should contact their GP or diabetes specialist nurse if they experience: Severe, persistent vomiting preventing adequate fluid intake (risk of dehydration and acute kidney injury) Severe abdominal pain, particularly if radiating to the back (potential pancreatitisrare but serious) Right upper abdominal pain, fever, or yellowing of skin/eyes (potential gallbladder disease) Sudden vision changes (particularly with semaglutide, which may worsen diabetic retinopathy, especially with rapid HbA1c reduction) [40] [41] Signs of hypoglycaemia when used with insulin or sulphonylureas Allergic reactions (rash, difficulty breathing, facial swelling)call 999 or go to A&E for severe allergic reactions Patients should report suspected side effects via the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk or the Yellow Card app)
In some cases, individuals might continue with regular B12 injections as a part of their long-term weight management strategy, especially if they notice a drop in energy or a plateau in their weight loss progress
Neurobion Injection is typically administered intramuscularly by a healthcare professional
In the late 1980s, open-label trials established the efficacy of apomorphine injection and infusion (Figure 4) in overcoming refractory off periods as well as attenuation of dyskinesia in PD
