Populations of particular concern based on ingredient mechanism and the absence of adequate human data include: individuals with Wilson's disease or other copper metabolism disorders
no significant adverse events have been observed in clinical trials
doi: 10.20517/cdr.2022.18 3 BullESinghAHardenASoanesKHabashHToracchioL
(Source 1) Vitamin C supplementation also increases Bifidobacteria , a genus of beneficial bacteria in the gut, and positively modulates the microbiome
Cells were then incubated overnight at 4C with different pairs of the following antibodies: mouse anti H2AX (Millipore cat.# 05-636), rabbit anti ICP8 antibody (kindly provided by prof WT Ruyechan, Univesity of Buffalo, Buffalo, NY, USA), as primary antibodies and Cy2-conjugated donkey anti-rabbit IgG and Alexa Fluor 568 donkey anti-mouse IgG (Molecular Probes, Life Technologies), as secondary antibodies (30 min at room temperature)