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Whilst the NHS notes that taking up to 2,000 micrograms daily is unlikely to cause harm in most people, there is generally no benefit to consuming such excessive amounts unless treating confirmed deficiency under medical supervision

While specific studies on the arginate form in neural tissue are limited, the shared mechanism of action suggests similar potential

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Experimental studies demonstrated that modulation of NNMT pathways could influence metabolic signaling networks involved in cellular energy utilization and body composition regulation