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422 Some studies also showed that HER2 heterogeneity correlated with worse clinical outcomes, 423 and HER2 intra-tumoral heterogeneity could be another potential factor for the resistance to anti-HER2 therapy
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In those patients, subjective improvement in GI symptoms typically appears within the first 30 days of a subcutaneous BPC-157 protocol
More targeted CNS uptake has been attempted by conjugating polymeric nanoparticles with ligands like transferrin or lactoferrin (Zha et al., 2024
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