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Evidence suggested that B cell and plasma cell activation leads to the production of DSAs, which can bind to HLA or non-HLA molecules expressed on the endothelial cells of the transplanted kidney (29, 30)
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They work well but differ in how they might suit patients
SNAP-8 (acetyl octapeptide-3) and botulinum toxin (Botox) both target the SNARE complex that triggers facial muscle contractions, but through different routes
Intriguingly, the underpinnings of AUD stages involve multiple signals that may diverge and overlap to some extent
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