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It was discovered that one of their side effects is weight loss, so they were used for this purpose for those who suffer from obesity when traditional methods, such as diet and exercise, fail
GRB2 depletion leads to fork collapse, cytosolic DNA accumulation, cGASSTING activation, and increased PARPi sensitivity
Zhang L, Falla TJ
As stated above, it has been reported that up to one-third of oral mucosal melanoma arise within fields of benign melanin hyperpigmentation [15, 4749]
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