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Researchers working with KLOW should maintain documentation of the research purpose and institutional context of use, consistent with standard laboratory materials management practices
doi: 10.1016/j.clinthera.2014.11.008 5 KlonoffDCBuseJBNielsenLLGuanXBowlusCLHolcombeJHet al
Deficiency in co-factors for the enzyme result in greatly increased lactic acid (in functional B2 deficiency) or pyruvate (in functional B1 deficiency)
None of these investigations comprehensively assess the effect of Gilberts syndrome on the full PK and metabolite profiles of paracetamol
It acts like a control centre, sending signals that tell the vessels when to widen (dilate) or narrow (constrict)
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