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Antibody Fab fragments are useful tools for structural characterization of target proteins and were used recently to obtain the first crystal structure of the glucagon receptor ECD and a new crystal structure of the glucose-dependent insulinotropic polypeptide (GIP) receptor ECD 28,29
2.*** Frauca Remacha E, Muoz Bartolo G
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Without identifying which mechanism is dominant, treatment is essentially guesswork
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