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Expert Rev Neurother 8:781797
The specific packaging varies - some use gel ice packs, others use phase-change materials that maintain temperature more precisely - but all attempt to keep the medication within safe temperature ranges during transit
In infants, signs of a vitamin B12 deficiency include failure to thrive, problems with movement, delays in reaching the typical developmental milestones, and megaloblastic anemia
Potential cardiovascular benefits (under investigation)
Therefore, there has been an emergence of the concept of using neoadjuvant therapy to eradicate tumors and avoid surgery completely
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