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A: Yes, rare but serious side effects of Tirzepatide Subcutaneous Route include anxiety, bloating, blurred vision, change in vision, changes in behavior, chest tightness, chills, cold sweats, coma, confusion, constipation, cool, pale skin, cough, darkened urine, depression, dizziness, fast heartbeat, fever, increased hunger, indigestion, large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs, loss of appetite, nausea, nervousness, nightmares, pains in the stomach, side, or abdomen, possibly radiating to the back, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, seizures, shakiness, slurred speech, thoughts of harming oneself, and unusual tiredness or weakness