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Adding to our concerns about potential abuse and overuse of the new GLP-1RA medications is the increasing medicalization of pediatric conditions [Reference Marty, Alvey, Mann and Murphy17], many of which result from environmental and societal rather than biological mechanisms, and the lack of progress in particular made in addressing the environmental and lifestyle issues that have contributed immeasurably to the childhood obesity epidemic
18 Access Access to GLP1 receptor agonists has proven to be challenging for many individuals for two main reasons: cost and available supply of the drugs themselves
Anyone interested in weight management pharmacotherapy should consult their GP or a registered specialist, who can discuss currently approved and evidence-based options available through legitimate NHS or regulated private pathways
In large-scale studies, semaglutide (the active ingredient in Ozempic and Wegovy) led to an average placebo-corrected weight loss of about 12.4% at the 2.4 mg dose
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