158 MRP4 and MRP5 facilitate the efflux of cyclophosphamide and 5-fluorouracil and are transcriptionally regulated by Nrf2 signaling and therapeutic stress
The chart below shows the thiamine content of some of the best sources ( In contrast, fruits, vegetables and dairy products generally do not provide much thiamine
Ikemoto, S., Takahashi, M., Tsunoda, N., Maruyama, K., Itakura, H., & Ezaki, O
Its been used for decades as an antidepressant (Wellbutrin) and a smoking cessation aid (Zyban)
GLP-1 receptor agonists slow gastric emptying and intestinal transit as part of their mechanism of action, which can lead to constipation in more than 1 in 10 people taking higher doses for weight management