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When the attack occurs, the blood supply to part of the brain is reduced or cut off, resulting in rapid and extensive cell death
The titration process for both medications is designed to minimize these side effects
At a genome-wide significant level, three loci (ABCG2, SLC2A9, and CUX2) have been identified in association with renal urate overload, whereas four loci (ABCG2, SLC2A9, CUX2, and GCKR) have been linked to renal urate underexcretion
Oncogenic risk from IGF-1 pathway activation
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Dev Neurosci 33(5):451467
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