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Thermogenesis 101: How Your Body Makes Heat Your body has a built-in heating system called thermogenesis
PMID 23000625
Sulfonylurea drugs affect sulfonylurea receptor 1 (SUR 1), which leads to the closure of adenosine triphosphate (ATP)-dependent potassium channels, preventing potassium from leaving the cell and depolarizing the cell membrane, leading to an influx of calcium and triggering insulin release
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