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They work by mimicking a hormone the body naturally has, called GLP-1
While some preclinical studies and small human trials have suggested that certain probiotic strains might influence circulating GLP-1 levels, the clinical significance of these changes for weight management is uncertain
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10.1016/j.jpsychires.2019.10.006 19 LavignaG.MasoneA.BouybayouneI.BertaniI.LucchettiJ.GobbiM.et al (2021)
The recommended starting dose is 0.25 mg (0.05 mL) once weekly for 4 weeks to improve gastrointestinal tolerability, then increase to 0.5 mg (0.10 mL) once weekly
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