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But access alone is not enough

Patients undergoing treatment for head and neck cancers, oral cancer, thyroid cancer, or brain tumors are particularly vulnerable to developing chronic dry mouth due to their treatment protocols

These include genes that drive oncogenicity via amplification 40 such as LMO1 (4 patients), CCND1 (3 patients), MYCN (2 patients) as well as MYC , MDM2 , MDM4 and NKX2-1 (1 patient)

Many foundational studies involved small numbers of subjects, appropriate for mechanistic pharmacology but insufficient for efficacy or safety conclusions

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