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In a 24-week phase 2 study investigating the effects of mazdutide on Chinese participants with overweight or obesity, there is a dose response effect, with a mean weight loss of 7.2%, 10.6%, and 11.6% at 3.0 mg, 4.5 mg, and 6.0 mg, respectively, compared to 1.0% with placebo (88)
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A comorbidity is mentioned casually, not coded or assessed: Insurers often look for clean charting, not implied history
These medications bind to GLP-1 receptors throughout the body, including in the pancreas, brain, and gastrointestinal tract, slowing gastric emptying and promoting satiety
In addition, the blood pressure of tails was not significantly different between the control and BPC 157 groups either 5,6
