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This combo can ease symptoms of both deficiencies

No significant functional changes expected yet

This study clarifies a critical variable in gerotherapeutics: the route and duration of administration do not simply alter the magnitude of a drugs efficacy

However, the administered NA dose was based on efficiency in hypercholesterolemia studies, therefore, an optimal NA dose for mitochondrial myopathy has to be determined, especially considering that another study found an association between metabolites of excess NA, 2PY, and 4PY, and cardiovascular disease (CVD) 245

Persistent or worsening symptoms beyond the initial treatment period should prompt medical review