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The study received funding from Wellcome, Medical Research Council, European Union Horizon 2020 Programme, the National Institutes of Health (grants U01-DK105535, U01-DK085545 and UM-1DK126185), the National Institute for Health Research Oxford Biomedical Research Centre, the Canadian Institutes of Health Research, the Novo Nordisk Foundation, Boehringer Ingelheim and Diabetes Australia.

Absence of early results in a supervised clinical setting is information that leads to protocol adjustment, not continuation without review

Numbness, tingling or burning sensation in the hands and feet are the symptoms of nerve damage

Pain presents on the top of the wrist and may radiate up the forearm

Dan Wool and affiliates make no effectiveness claims about supplements, hormones, peptides or other therapeutics beyond cited clinical evidence and regulatory approval