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Since GLP-1 acts on multiple pathways that are not fully addressed by other therapies, GLP-1 receptor agonists (drugs that mimic GLP-1 to improve insulin response and reduce glucose levels) have become the foundation for medications used in modern diabetes management 3
Site-specific incorporation of the expressing construct is an improved option, but this approach is very arduous, particularly when the genomic DNA sequences of genes that span large genomic regions are used
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