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The death of motor neurons results in a characteristic clinical feature: spasticity, muscular weakness and atrophy, hyperreflexia, cramps, fasciculation, Babinski sign, loss of coordination, paralysis of voluntary musculature, dysphagia and difficulties in swallowing, speech and respiration (Weiduschat et al., 2014
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It stops and controls the production of melanin
Rushing through titration increases the likelihood of discontinuing treatment due to intolerable symptoms
So it turns out these hormones are just key physiologic signals
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