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Gastrointestinal side effects are the most commonly reported and include: Nausea (affecting 1040% of patients, depending on the specific GLP-1 agonist) Vomiting and diarrhoea (less common than nausea but can contribute to dehydration) Constipation (due to slowed gastric emptying) Abdominal discomfort or bloating These effects are typically most pronounced during treatment initiation and following dose increases
Patients with uncontrolled cardiovascular conditions should discuss caffeine limits with their healthcare provider
However, until randomized clinical trials of these pharmacologic tools for obesity and metabolic dysfunction evaluate asthma outcomes as a primary endpoint, the costly management of comorbid asthma in adults with obesity will still heavily rely on the paradigm of inhaled ICS with or without LABA
What Is a Peptide
Lustig to weave these threads together into a novel unifying hypothesis regarding the etiology, prevention, and treatment of the current obesity epidemic, and the role of our environment in the biochemical changes that promote weight gain
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