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Histological features include epidermal atrophy and increased number of melanocytes
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Regarding GLP-2, Gu and colleagues evaluated a modified GLP-2 analog in mice, demonstrating that it reduced disease severity by restoring epithelial junctions and barrier integrity (87), complementing their currently approved use of GLP-2 analogs in short bowel syndrome (88, 89)
These changes compromise granulosa cell support, impair meiotic progression, and accelerate ovarian aging, contributing to female infertility disorders such as polycystic ovary syndrome
Review of Cardiovascular Outcomes Trials of Sodium-Glucose Cotransporter-2 Inhibitors and Glucagon-Like Peptide-1 Receptor Agonists
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