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This mechanism is called the carnitine shuttle, in which fatty acids cross the mitochondrial membranes bound to L-carnitine, forming acylcarnitine molecules that can cross the mitochondrial membrane through a transporter in exchange for free L-carnitine
Slower Digestion : By slowing gastric emptying, GLP-1 reduces blood sugar spikes and prolongs the feeling of fullness after meals
All of these studies are hypothesis-generating and await confirmation in RCTs. According to Lane, the rationale for GLP-1 receptor agonists in lupus stems from the drugs demonstrating anti-inflammatory properties, potentially by inhibiting the NF-B pathway, which plays a crucial role in inflammation
Visse, R
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