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Many trauma centers now specifically ask about GLP-1 agonists as part of their standard anesthesia assessment, but identification ensures the information reaches your team

In addition, in the cases of methylmalonic acidemia with homocystinuria due to pathogenic variants in the methionine synthase (MTR) gene the consequent reductions in S-adenosylmethionine (SAM or AdoMet) synthesis results in loss of efficient phospholipid methylation leading to defects in myelin sheath membrane lipid homeostasis which contributes to the neural pathology of these disorders

NOTE : They used venous blood samples to do the OGTT, but kept tabs on the glucose levels across the day, with the help of a CGM (continuous glucose monitoring device)

Cases of acute renal failure following treatment with DPP-4 inhibitors are rare (101)

PMID 10233312