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Body weight In comparisons vs placebo, tirzepatide was the most efficacious medication for lowering body weight, resulting in reductions ranging from 9.57 kg (95% CI 8.36, 10.78) with tirzepatide 15 mg to 5.27 kg (95% CI 3.98, 6.56) with tirzepatide 5 mg (Fig

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Both drugs were on the FDA drug shortage list, and both have FDA-approved branded versions (Ozempic, Wegovy, Mounjaro, Zepbound)

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