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Biochemical and Biophysical Research Communications Endogenous GLP-1 acts on paraventricular nucleus to suppress feeding : Projection from nucleus tractus solitarius and activation of corticotropin-releasing hormone, nesfatin-1 and oxytocin neurons

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There's still a lot of work to do, however, to improve public health in the US and around the world, where obesity rates remain high: 28 percent as reported in the UK in 2022, and 31.7 percent in Australia in 2022-23

For a deeper look at how semaglutide, a GLP-1 receptor agonist, compares to tirzepatide, a dual GLP-1 and GIP receptor agonist, read our comparison guide on semaglutide vs