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Autocrine transforming growth factor beta suppresses telomerase activity and transcription of human telomerase reverse transcriptase in human cancer cells
Initially conceptualized as a therapeutic for neurodegenerative disorders such as Alzheimers and Parkinsons disease, its primary mechanism of action involves high-affinity binding to hepatocyte growth factor (HGF) and its cognate receptor c-Met
Many offerings are verified at over 99% purity , and documentation is provided to support research needs and internal lab requirements
The specific antisense sequences were 5-GGCUCCUACACUUCUGUUATT-3 for FoxO4 siRNA and 5-UAACAGAAGUGUAGGAGCCTT-3 for the negative control
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