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It is critical to emphasise that dedicated cardiovascular outcomes trials (CVOTs) the gold standard for assessing a drug's long-term effect on events such as heart attack and stroke have not yet been completed for retatrutide
In contrast, the glucose-lowering effect of T3 treatment could not be observed in the hypothyroid mice four hours after injection of a single dose of T3 (MMI + T3-4h mice), although these mice displayed very high levels of circulating T3 (Supplementary Fig
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