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This delay in treatment initiation and intensification, known as treatment inertia or clinical inertia, poses a significant risk of diseases and comorbidities associated with T2DM
However, the FDA does not review compounded medications for safety, effectiveness, or quality before they are marketed
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GLP-1RAs can exert not only anti-inflammatory effects in the endothelium, but also anti-apoptotic effects aimed at maintaining endothelial homeostasis
Since metabolic weight loss requires remaining on the maintenance dose for several months or years, this represents a massive, predictable price hike for every successful patient
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