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Nature 539, 390395
The strategy works best when the reformulation provides a genuine clinical benefit, not merely a convenience difference
Cpsula: praticidade e dosagem controlada para o dia a dia
As shown in Figure 8, eucalyptol was able to interact with CAT residues through hydrogen bond interactions with His194, in addition to several hydrophobic interactions with Pro151, Ile152, Phe198, Val302, Phe446, and Val450
About 20% of the population has coagulation defects, making them more susceptible to abnormal coagulation
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