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The formulation pairs a stabilized GHRH receptor agonist with a selective growth hormone secretagogue receptor (GHS-R) agonist, allowing concurrent investigation of GHRH and ghrelin / GHS pathway activation

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Both studies used the ingredient at 0.1% which also matches how much it usually shows up in products (at fractions of a percent)

Additionally, the review highlights the utility of PLGA nanoparticles in delivering phytochemicals with neuroprotective effects such as polyphenols, flavonoids, and coumarins to overcome challenges associated with their solubility and stability and ultimately enhance their activities for managing PD

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