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Recent Mendelian randomization findings further validate this framework: Dorea and Sellimonas appear protective, whereas Phascolarctobacterium and Ruminococcaceae UCG-004 are associated with increased PTSD risk (He et al., 2024)

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This toxicity can also cause kidney failure and pancreatitis, which can be deadly if left untreated

MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis Nature Communications (2021) 7

Common timing: before bed (to amplify the natural nocturnal GH pulse), upon waking, and/or post-exercise