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We acknowledge the risks involved in taking medications, but it is equally important to consider the risks associated with obesity
Zepbound (tirzepatide) is a glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist that is FDA-approved along with increased physical activity and a reduced-calorie diet for chronic weight management in adults with a starting body mass index (BMI) of: 30 kg/m^2 or higher (obesity) or 27 kg/m^2 or higher (overweight) with at least one weight-related condition such as high cholesterol, high blood pressure (hypertension), type 2 diabetes, heart disease, or obstructive sleep apnea
At the same time, some people taking GLP-1s have experienced acute kidney injuries
However, this mechanism also slows down the process of moving food through your intestines, sometimes resulting in constipation while your body adjusts to the medication
10.1093/eurheartj/ehab169 Eur Heart J
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