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Expression of E-cadherin cell adhesion molecules suppresses melanocyte proliferation, but on the other hand, expression of N-cadherin triggered by trauma or metabolic changes in the microenvironment promotes proliferation and migration of melanocytes, which can then aggregate in nests [4, 6]
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In one of the landmark studies that supported the use of this drug for weight loss, the individuals who were on the drug actually lost a meaningful amount of lean mass, not just fat mass
Journal Sports Medicine 13 (1), 23259671241297157
