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Diabetes 46 (5), 824828

Esta accin la sita en el centro del metabolismo energtico, especialmente en tejidos que dependen en gran medida de los lpidos como combustible, como el msculo cardaco y el esqueltico

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The protection appears to result from the peptide's ability to bypass inhibitory IGFBP interactions, allowing more effective activation of IGF-1 signaling pathways that enhance sarcolemmal stability and reduce membrane damage during eccentric contractions

Technologies such as BioID and APEX labeling are uncovering how subcellular localization influences proteostasis pathway coordination